Metabolomics application in maternal-fetal medicine

Metabolomics in maternal-fetal medicine is still an "embryonic" science. However, there is already an increasing interest in metabolome of normal and complicated pregnancies, and neonatal outcomes. Tissues used for metabolomics interrogations of pregnant women, fetuses and newborns are amniotic fluid, blood, plasma, cord blood, placenta, urine, and vaginal secretions. All published papers highlight the strong correlation between biomarkers found in these tissues and fetal malformations, preterm delivery, premature rupture of membranes, gestational diabetes mellitus, preeclampsia, neonatal asphyxia, and hypoxic-ischemic encephalopathy. The aim of this review is to summarize and comment on original data available in relevant published works in order to emphasize the clinical potential of metabolomics in obstetrics in the immediate future

Non-linear water waves generated by impulsive motion of submerged obstacles

A fully non-linear problem on unsteady water waves generated by an impulsively moving obstacle is studied analytically. Our method involves reduction of the Euler equations to the integral-differential system for the wave elevation together with normal and tangential fluid velocities at a free surface. Exact model equations are derived in explicit form in a case where an isolated obstacle is presented by a totally submerged elliptic cylinder. A small-time asymptotic solution is constructed for a cylinder which starts with constant acceleration from rest. It is demonstrated that the leading-order solution terms describe several wave regimes such as the formation of non-stationary splash jets by vertical rising or vertical submersion of the obstacle; the generation of diverging waves is also observed

Bounce Loop Quantum Cosmology Corrected Gauss-Bonnet Gravity

We develop a Gauss-Bonnet extension of Loop Quantum Cosmology, by introducing holonomy corrections in modified $F(\mathcal{G})$ theories of gravity. Within the context of our formalism, we provide a perturbative expansion in the critical density, a parameter characteristic of Loop Quantum Gravity theories, and we result in having leading order corrections to the classical $F(\mathcal{G})$ theories of gravity. After extensively discussing the formalism, we present a reconstruction method that makes possible to find the Loop Quantum Cosmology corrected $F(\mathcal{G})$ theory that can realize various cosmological scenarios. Specifically, we studied exponential and power-law bouncing cosmologies, emphasizing on the behavior near the bouncing point and in some cases, the behavior for all the values of the cosmic time is obtained. We exemplify our theoretical constructions by using bouncing cosmologies, and we investigate which Loop Quantum Cosmology corrected Gauss-Bonnet modified gravities can successfully realize such cosmologies.Comment: Revised version, to appear in PR

Measuring the Luminosity of a gamma gamma Collider with gamma gamma -> l+ l- gamma Events

The process gamma gamma -> l+ l- is highly suppressed when the total angular momentum of the two colliding photons is zero so that it cannot be used for luminosity determination. This configuration, however is needed for Higgs production at a photon collider. It will be shown that the process gamma gamma -> l+ l- gamma can be used in this case to measure the luminosity of a collider with a precision that is good enough not to limit the error on the partial decay width Gamma(H -> gamma gamma).Comment: Final version, accepted by journa

Internal waves in marginally stable abyssal stratified flows

The problem on internal waves in a weakly stratified two-layer fluid is studied semi-analytically. We discuss the 2.5-layer fluid flows with exponential stratification of both layers. The long-wave model describing travelling waves is constructed by means of a scaling procedure with a small Boussinesq parameter. It is demonstrated that solitary-wave regimes can be affected by the Kelvin–Helmholtz instability arising due to interfacial velocity shear in upstream flow.</p

Rapid convergence of time-averaged frequency in phase synchronized systems

Numerical and experimental evidence is presented to show that many phase synchronized systems of non-identical chaotic oscillators, where the chaotic state is reached through a period-doubling cascade, show rapid convergence of the time-averaged frequency. The speed of convergence toward the natural frequency scales as the inverse of the measurement period. The results also suggest an explanation for why such chaotic oscillators can be phase synchronized.Comment: 6 pages, 9 figure